![]() ![]() In addition, the solution used in hemodialysis unit contains formalin. It is benefited from formaldehyde for the structure of coatings in dentistry, in the clinic for the treatment of persistent cystitis, and as a preservative in some drugs. Formaldehyde, which has an important place in the field of medicine, is used in the anatomy laboratory for the determination of the cadaver and its long-term storage without decomposition and used in histology and pathology laboratories during the fixation stage of tissues. Also, it is used as disinfectant because it kills insects and many microorganisms. įormaldehyde is used in the storage of biological samples and mummification as it hardens proteins and prevents them from decomposition. It is used in the industrial field in the construction of plywood, chipboard, insulation materials, paint and plastic materials, textile industry, carpets, furniture, wall coverings, and household cleaning products. It is particularly important in the chemical industry because formaldehyde is an inexpensive starting material for a number of chemical reactions. įormaldehyde is a chemical that is widely used due to its chemical properties and is also found in the natural structure of the organism. In addition, formaldehyde shows antimicrobial activity and function detection in tissues that have lost their vitality. This combination causes cytotoxicity, inflammatory reaction, necrosis, allergy, and mutagenic effect to be seen by producing denaturation in proteins. Formaldehyde tends to combine strongly with protein, nucleic acids, and unsaturated fatty acids in a nonenzymatic way. Formaldehyde is excreted from the body through urine and stool, by metabolizing formic acid catalyzed formaldehyde dehydrogenase (FDH) enzyme in the liver and erythrocytes, or excreted through respiration by converting to carbon dioxide. įormaldehyde is found in small quantities in every human cell because it is taken from outside the organism or it is derived from the metabolism of serine, glycine, choline, and methionine. The most sensitive of these methods is flow injection, which has a detection limit of 9 ppt (0.011 μg/m 3) and is high-performance liquid chromatography, which offers a detection limit of 0.0017 ppm (0.002 mg/m 3). Organic and inorganic chemicals, such as sulfur dioxide, other aldehydes, and amines, can interfere with these detection methods. Besides spectrophotometric ways other methods such as high-performance liquid chromatography, gas chromatography, colorimetry, infrared detection, fluorimetry, polarography, and gas detector tubes are also used. The most common methods for formaldehyde detection are based on spectrophotometry. ![]()
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